NJ-DMDG

2018 Fall Symposium & Vendor Exhibition

Sponsored by the

North Jersey ACS Drug Metabolism Discussion Group

“Strategies for Optimizing Pharmacological, Metabolic, and Toxicological Profiles of Clinical Candidates

Date:   October 11, 2018

Time:   8:00 am – 3:45 pm

Venue:  The Palace at Somerset Park,
        333 Davidson Avenue,
        Somerset, NJ 08873     [ directions ]

NJDMDG Fall Symposium 11 Oct 2018

Speakers & Organizers: Bottom row (L to R): Matt Hoffman (Celgene), Beth Joshi (Merck), Laura Armstrong (Rutgers), Piyush Bajaj (Takeda), Judi Wardwell (InSphero), Li Yu (Roche), Top row (L to R): Murat Cirit (MIT), Imad Hanna (Novartis), Naiyu Zheng (BMS), Dan Mudra (Lilly), Wing Lam (Janssen), Fan Wu (Celgene)

Registration Information:

  • Pre-registration fee is $125 (pre-register by October 5, 2018).
  • Registration fee at the door is $150 (Checks only)
  • Registration fee is $10 for students and postdocs and $50 for faculty
  • Registration is free for unemployed

Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG Steering Committee List, below, from your organization.

  • If you have no DMDG member at your company, please contact Elizabeth Joshi (elizabeth.joshi@merck.com) for registration.
  • Payments by personal or company checks. Sorry, credit cards are not accepted.
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.

Exhibitors:

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2009 Fall Symposium and Vendor Exhibition





Program




“Strategies
for Optimizing Pharmacological, Metabolic, and Toxicological Profiles of
Clinical Candidates”


8:00
a.m.



Registration
/ Continental Breakfast / Vendor Exhibit


9:00
a.m.



Introductory Remarks




Elizabeth Joshi,
Chair, NJ DMDG



9:15
a.m.



Mechanistic Modeling at the Discovery-Development Interface: From Design to Dose






Daniel Mudra,

PhD, Director, Discovery ADME, Eli Lilly and Company






10:00
a.m.



Translational DMPK
Applications of Tissue Chip Technologies




Murat Cirit,
PhD, Director, Translational
Center of Tissue Chip Technologies at Massachusetts Institute of Technology
(MIT)


10:45 a.m.




Vendor Exhibit & Coffee
Break



11:15
a.m.



Microphysiological
multi-tissue flow-based system utilizing InSphero 3D InSight™ Microtissues:
Applications for DMPK, Drug Metabolism and Drug Discovery




Judi Wardwell,
Senior Technical
Specialist, InSphero Inc.


12:00 p.m.




Lunch & Vendor Exhibit



1:20
p.m.



Model-informed
translational strategies to improve upon drug safety risks






Piyush Bajaj,
PhD, Scientist II
– Investigative Toxicology, Drug Safety Research and Evaluation,

Takeda, Cambridge, MA


2:05 p.m.



Hepatic FXR’s
Protective Role Against NASH Development in a High-Fat Diet Induced NAFLD
Mouse Model






Laura Armstrong,
PhD,
Post-Doctoral Research Fellow, Rutgers University


2:35 p.m.




Vendor Exhibit & Coffee
Break



3:00 p.m.



Novel Metabolite
ID Platform for Therapeutic Proteins




Xiang Yu,
PhD, Associate
Principle Scientist, PPDM Preclinical ADME Metabolite




ID,
Merck, West
Point, NJ





3:45
p.m.




Program






Closure





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NJ-DMDG Steering Committee 2018-2019
Name Company E-mail address Responsibility
Beth Joshi Merck elizabeth.joshi@merck.com Chair, 2018-19
Imad Hanna Novartis imad.hanna@novartis.com Chair Elect, 2019-20
Matthew Hoffmann Celgene mjhoffman@celgene.com Treasurer
Naiyu Zheng BMS naiyu.zheng@bms.com Vendor Liaison
Manthena Varma Pfizer Manthena.V.Varma@pfizer.com Past Chair, 2017-18
Bo Wen GSK bo.1.wen@gsk.com Past Chair, 2016-17
Lauren Aleksunes Rutgers University aleksunes@eohsi.rutgers.edu Past Chair, 2015-16
Wing Lam Janssen R&D wlam@its.JnJ.com Past Chair, 2013-14
Allen Jones allen.n.jones@verizon.net Past Chair, 2012-13
Anima Ghosal Kean University ghosala@aol.com Member
Ron Kong PTC Therapeutics rkong@ptcbio.com Member
Lei Tang Sanofi Lei.Tang@sanofi.com Member
Li Yu Roche li.yu.ly1@roche.com Member
Fan Wu Celgene fwu@celgene.com Member
Jin Wu Merck Jin_wu@merck.com Member
Zhao pie Zeng zhaopiezeng@gmail.com Member
Carolina Berthiaume carolina.berthiaume@gmail.com Member
Maria Markowska Mmaryla5@yahoo.com Member

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Directions to the Palace at Somerset Park

    333 Davidson Avenue, Somerset, NJ 08873

    Phone: 732-302-9922
    [ website ]

From the New Jersey Turnpike:

    Exit 10 to Interstate 287 North.
    Follow 10 miles to Exit 10 (527 New Brunswick — South Bound Brook).
    Take Easton Ave towards South Bound Brook to first light,
    make left (Davidson Ave.)

From New York City:

    Lincoln Tunnel to N.J. Turnpike South.
    Follow N.J. Turnpike directions mentioned above.

From Route 287:

    If traveling north:

      Exit 10 (527 New Brunswick — South Bound Brook).
      Follow sign towards Bound Brook, to light
      make left (Davidson Ave.)
    If traveling south:

      Exit 10 (527 New Brunswick).
      Left on Easton Ave., to light,
      make left (Davidson Ave).

From Newark Airport:

    Take NJ Turnpike South to Exit 10
    I-287 North to Exit 10 (Easton Ave)
    at first light, go left on Davidson Ave.
    Hotel immediately on left.

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