The NJ Mass Spectrometry Discussion Group is pleased to announce our March 2020 Monthly Meeting.
NJ MSDG is the second largest mass spectrometry professional association in the nation behind ASMS, with over 1,100 members in the tristate area. [ homepage ]
Date: Tuesday March 10, 2020
Venue: Somerville Elks Lodge 1068
375 Union Avenue, Bridgewater, NJ 08807
908-707-1545
[ http://somervilleelks.org ]
Sponsor: Agilent Technologies
Please register here. Registration is free, compliments of our sponsor.
Program
5:30 PM Social and Registration
6:15 PM Complimentary Dinner
6:55 PM Welcome and Opening Remarks
7:05 PM Speakers
Speaker 1: Jim Arndt, PhD
Applications Scientist, MOBILion Systems, Inc.
“Structures for Lossless Ion Manipulations (SLIM) for the Masses”
Abstract for Jim Arndt:
Abstract: Structures for Lossless Ion Manipulation (SLIM) is a high-resolution ion mobility technique that enables ion packets to be transmitted around corners enabling several meters of separation in a small footprint without ion loss during separation1-3. In the last year, MOBILion Systems, Inc. has developed, and will commercialize, a thirteen-meter SLIM device coupled exclusively to Agilent Q-ToF systems. In our product overview seminar we will dive into our technical development and innovation efforts that are leading to the commercial product, with emphasis on proof-of-concept data in life science markets. Discussions will include lipidomics, clinical research testing, and biologic therapeutic characterization.
Speaker 2: Qing Wang, PhD, MHS, MS
Founder and CEO, Complete Omics Inc.
“Direct Detection and Quantification of Neo-antigens”
Abstract for Qing Wang:
Abstract: Many immunotherapeutic approaches under development rely on T-cell recognition of cancer-derived peptides bound to human leukocyte antigen molecules on the cell surface. Direct experimental demonstration that such peptides are processed and bound is currently challenging. Here we described a method that meets this challenge. The method entailed an optimized immuno-precipitation protocol coupled with two-dimensional chromatography and mass spectrometry. The ability to detect and quantify minute amounts of pre-defined antigens should be useful for both basic research in tumor immunology as well as for the development of rationally-designed cancer vaccines.
