“Drug Metabolism/Transport Interplay: Regulatory, Therapeutic and Toxicological Implications”

Somerset Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey

October 13, 2010
8:00 am – 3:45 pm

Program

08:00 am
Registration / Continental Breakfast / Vendor Exhibit

09:00 am
Introductory Remarks
Dr. Imad Hanna, Chair, NJDMDG [slides (PDF)]

09:10 am
Regulation of Renal Drug Transport under Physiological and Pathological Conditions [slides (PDF)] Dr. Rosalinde Masereeuw, Associate Professor, Department of Pharmacology and Toxicology, Radboud University Nijmegen Medical Centre, The Netherlands

10:00 am
Pharmacokinetic Determinants of Statin-Induced Myopathy [slides (PDF)] Dr. Rommel G. Tirona, Assistant Professor, Department of Physiology and Pharmacology, The University of Western Ontario, London, Ontario

10:45 am
Vendor Exhibit & Coffee Break

11:30 am
Membrane Transporters in Drug Development [slides (PDF)] Dr. Raymond Evers, Director, Transporters and In Vitro Technologies, Drug Metabolism and Pharmacokinetics, Merck and Co. Rahway, NJ.

12:15 pm
Lunch & Vendor Exhibit

01:45 pm
Regulatory Interplay between Vitamin D and CYP3A4 in the Small Intestine
Dr. Kenneth E. Thummel, Professor and Chair, Department of Pharmaceutics, University of Washington, Seattle, WA.

02:30 pm
Vendor Exhibit & Coffee Break

03:00 pm
Inter-Individual Variability in Human Drug Glucuronidation: What We Know and What We Need to Know [slides (PDF)] Dr. Michael H. Court, Associate Professor, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA.

03:45 pm
Program Closure