Mar 25, 2021 – NMR Topical Group Meeting

Structural details often provide molecular mechanisms to construct the interplay among biology, chemistry and engineering for drug product development. Solid-state NMR analyzes a wide range of drug and wet pharmaceutical materials from small molecule medicines to biological products. The obtained structural information at macroscopic and microscopic scales offer critical knowledge for understanding and optimizing drug delivery, chemical and physical stability, bioavailability, formulation composition, and manufacturing process. This presentation will provide examples to introduce the molecular structure mediated questions in pharmaceutical sciences and elaborate how ssNMR techniques are employed to tackle these analytical challenges.